Kobayashi reported a score for determining the efficacy of therapy for obstetrical disseminated intravascular coagulation (DIC). One component is based on laboratory test findings. The author is from Hamamatsu Medical Center in Shizuoka, Japan.
Patient selection: pregnant woman
Laboratory testing is performed at presentation and after treatment.
Parameters:
(1) serum fibrin degradation products (FDP) in µg/mL (mg/L)
(2) platelet count per µL
(3) plasma fibrinogen in mg/dL
(4) prothrombin time (PT) in seconds
Parameter
Finding
Point
serum FDP
< 10 µg/mL
0
10 to 19 µg/mL
1
20 to 39 µg/mL
2
40 to 79 µg/mL
3
>= 80 µg/mL
4
platelet count
>= 200,000 per µL
0
160,000 to 199,999
1
120,000 to 159,999
2
80,000 to 119,999
3
< 80,000 per µL
4
plasma fibrinogen
> 200 mg/dL
0
150 to 200 mg/dL
1
100 to 149 mg/dL
2
50 to 99 mg/dL
3
< 50 mg/dL
4
prothrombin time
< 12 seconds
0
12 to 15 seconds
1
15.1 to 20 seconds
2
20.1 to 25 seconds
3
> 25 seconds
4
total score =
= SUM(points for all 4 parameters)
Interpretation:
• minimum score: 0
• maximum score: 16
• The higher the score the greater the laboratory abnormalities.
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