Bradley et al outlined options for the drainage of a parapneumonic effusion in a pediatric patient with community-acquired pneumonia (CAP). The authors are from the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America.
Patient selection: CAP with parapneumonic effusion
Parameters:
(1) size of effusion
(2) nature (simple vs complicated)
A small effusion without complications will usually resolve with antibiotic therapy and does not have to be drained.
Drainage tends to be needed for:
(1) moderate or large effusions
(2) loculated fluid
(3) respiratory distress
(4) purulent effusion (empyema)
Drainage options:
(1) chest tube alone (if without empyema and/or loculations)
(2) chest tube with fibrinolytic therapy
(3) video-assisted thoracoscopic surgery (VATS)
Fibrinolytic regimens:
(1) St Peter et al
(2) Hawkins et al
(3) Sonnappa et al
Parameters |
St Peter |
Hawkins |
Sonnappa |
---|---|---|---|
fibrinolytic agent |
tissue plasminogen activator |
tissue plasminogen activator |
urokinase |
dosing (made up in normal saline, NS) |
4 mg in 40 mL NS |
MIN(0.1 mg/kg, 3 mg) in 10-30 mL |
10,000 U in 10 mL if under 1 year old; 40,000 U in 40 mL if over 1 year old |
dwell time |
1 hour |
0.75 to 1 hour |
4 hours |
suction on chest-tube (in cm H2O) |
-20 |
-20 to –25 |
-10 to –20 |
number of times done |
3 |
9 |
6 |
dosage intervals |
24 hours |
8 hours |
12 hours |
where:
• During the dwell time there is no suction on the chest tube.
• The number of doses and the dosage intervals all add up to 3 days.
• In the Hawkins protocol the 3 mg is reached at a body weight of 30 kg.
Purpose: To manage a pediatric patient with community-acquired pneumonia (CAP) who has a parapneumonic effusion.
Specialty: Infectious Diseases, Pulmonology
Objective: options, surgery
ICD-10: J12, J13, J14, J15, J16, J17, J18,