PIRO (Predisposition, Insult/Infection, Response, Organ Dysfunction) Score of Rubulotta et al for Sepsis

age and comorbid

< 46 years old

0

46 to 64 years old without chronic liver disease

1

46 to 64 years old with chronic liver disease

3

65 to 85 years old without chronic liver disease or congestive cardiomyopathy

2

65 to 85 years old with congestive cardiomyopathy

3

65 to 85 years old with chronic liver disease

4

> 85 years old

4

sepsis source

community-acquired UTI, Gram negative bacteria

0

community-acquired UTI, not Gram negative

1

community-acquired infection, other than urinary

2

hospital-acquired infection, Gram positive

2

hospital-acquired infection, not Gram positive

3

hospital-acquired, fungal, not abdominal

3

hospital-acquired, fungal, abdominal

4

clinical response

no tachycardia and no tachypnea

0

either tachycardia or tachypnea but not both

0

both tachycardia and tachypnea

1

number of organ failures

0 to 2

0

3 with 1 hepatic

1

3 with none hepatic

2

4

3

5

4

0, 1, 2 or 3

21%

4

31%

5

40%

6

49%

7

57%

8

64%

9

72%

10 to 13

80%