The clinical severity and mortality risk of bacterial pneumonia in HIV-infected patients is associated with certain risk factors.
Patient population: HIV-infected patients treated at a university hospital (Universita Cattolica) in Rome, Italy
Risk factors associated with mortality:
(1) Karnofsky score, with debility associated with increased risk
(2) PaO2, with hypoxemia associated with increased risk
(3) CD4 cell count, with low counts associated with increased risk
(4) WBC count, with neutropenia associated with increased risk
|
Parameter |
Finding |
Points |
|
Karnofsky score |
> 50 |
0 |
|
|
<= 50 |
1 |
|
PaO2 |
> 70 mm Hg |
0 |
|
|
<= 70 mm Hg |
1 |
|
T cell CD4 count |
> 100 per µL |
0 |
|
|
<= 100 per µL |
1 |
|
PMN count |
> 3,000 per µL |
0 |
|
|
1,000 - 3,000 per µL |
1 |
|
|
< 1,000 per µL |
2 |
severity score =
= (points for Karnofsky status) + (points for PaO2) + (points for CD4 count) + (points for PMN count)
Interpretation:
• minimum score: 0
• maximum score: 5
|
Score |
Severity of Pneumonia |
|
0 or 1 |
mild |
|
2 or 3 |
moderate |
|
4 or 5 |
severe |
Purpose: To predict the severity of bacterial pneumonia in HIV-infected patients from clinical risk factors.
Specialty: Infectious Diseases, Pulmonology
Objective: risk factors, severity, prognosis, stage
ICD-10: B20.1,
