Tello et al reported a rule for estimating the risk of malignancy in an hepatic lesion identified on MRI. The authors are from Boston University.
Patient selection: hepatic lesion on MRI
Parameters:
(1) T2 relaxation time in milliseconds
(2) hemangioma-like on gadopentetate dimeglumine enhancement
(3) known malignancy
Parameter
Finding
Points
T2 relaxation time in milliseconds
0.0643 * (milliseconds)
enhancement on gadopentate dimeglumine
hemangioma-like
3.16
not hemangioma-like
0
known malignancy
no
0
yes
-1.9458
X =
= SUM(points for all 3 parameters) - 6.6769
probability that the lesion is benign =
= 1 / (1+EXP((-1) * X))
NOTE: The articles says that the last equation is for the probability of malignancy. However, the example given indicates that the equation is for benignity.
probability of malignancy =
= 1 - (probability of benignity)
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