Description

Stern et al developed an equation to identify a patient at high risk for type 2 diabetes mellitus based on logistic regression analysis. This can help identify a patient who should be a candidate for additional testing and closer monitoring. The authors are from the University of Texas Health Science Center in San Antonio.


Parameters:

(1) age of the patient in years

(2) body mass index in kilograms per square meter

(3) fasting glucose in mg/dL (not stated as plasma or whole blood)

(4) systolic blood pressure in mm Hg

(5) gender

(6) HDL cholesterol in mg/dL

(7) race

(8) family history of diabetes in parent or sibling

 

Parameter

Finding

Points

gender

male

0

 

female

1

race

Hispanic

1

 

non-Hispanic white

0

family history

negative

0

 

present

1

 

where:

• Blacks were not included in the study population.

 

X =

= (-13.415) + (0.028 * (age in years)) + (0.079 * (fasting glucose)) + (0.661 * (points for gender)) + (0.070 * (BMI)) - (0.039 * (HDL cholesterol)) + (0.481 * (family history)) + (0.018 * (systolic blood pressure)) + (0.412 * (points for race))

 

probability of diabetes =

= 1 / (1 - EXP((-1) * X))

 

NOTE: Almost all of the logistic regression equations I have seen have had the form P = (1 / (1 + EXP((-1) * X))). When the equation was implemented as described, unreasonable values are returned. More reasonable results are returned when the typical equation is used. It is interesting that this is the same apparent error as shown in Predictive Equation of Tabaei and Herman to Screen for Diabetes Mellitus.

 

alternative equation for probability of diabetes giving more reasonable results =

= 1 / (1 - EXP((-1) * X))


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