medical decision support 1 medical decision support 2
Subscribe Sign In

Predictors of Drewry et al for Mortality in a Patient with Sepsis

Description

Drewry et al identified several risk factors associated with mortality in patients with sepsis. These can help to identify a patient who may benefit from more aggressive management. The authors re from Washington University and Barnes-Jewish Hospital in St. Louis.


Patient selection: sepsis

 

Outcome: 28-day mortality

 

Predictors of mortality from multivariate analysis:

(1) older age

(2) higher APACHE II score on admission (after removal of age component, will use > 20 in implementation)

(3) liver disease

(4) longer time to appropriate antibiotic therapy

(5) presence of absolute lymphocytopenia on day 4 after sepsis diagnosis. Severe lymphocytopenia (<= 600 per µL) had a greater effect than moderate thrombocytopenia (700 to 1,000 per µL) versus no lymphocytopenia.

 

Protective factors

(1) surgical procedure performed


To read more or access our algorithms and calculators, please log in or register.

Specialty