Schmidt et al identified predictors for a poor outcome for an extremely low-birth-weight (ELBW) infant. The authors are from the Trial of Indomethacin Prophylaxis in Preterms (TIPP) investigators from Canada, the United States, New Zealand and Hong Kong.
Patient selection: preterm with birthweight 500-999 grams
Outcomes at 18 months: cerebral palsy, cognitive delay. severe hearing loss and/or bilateral blindness
Predictors:
(1) evidence of brain injury on ultrasonography (odds ratio 3.7)
(2) bronchopulmonary dysplasia (odds ratio 2.4)
(3) severe retinopathy of prematurity (odds ratio 3.1)
Number of Predictors
Poor Outcome at 18 Months
0
18%
1
42%
2
62%
3
88%
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