Patient selection: candidate for hepatic resection of colorectal metastases
Parameters associated with a worse overall survival on multivariate analysis:
(1) age > 70 years
(2) number of metastatic nodules >= 8
(3) preoperative ratio of neutrophils to lymphocytes >= 5
(4) largest size of tumor metastasis > 5 cm
ratio of neutrophils to lymphocytes =
= (percent neutrophils) / (percent lymphocytes) =
= (absolute neutrophil count) / (absolute lymphocyte count)
where:
• The number of tumor metastases is >= 8 in Table 1 but > 8 in Table 3.
• The percent neutrophils should include immature forms (bands, metamyelocytes).
The preoperative ratio of neutrophils to lymphocytes >= 5 also identifies a patient who is more likely to have tumor recurrence.
