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Probability of 28-Day Mortality for a Patient with Acute-on-Chronic Liver Failure (ACLF) Based on the Leukocyte Count

Description

Moreau et al evaluated patients acute-on-chronic liver failure and reported the relationship between the leukocyte count and mortality. This can help to identify a patient who may require more aggressive management. The authors are from multiple institutions in Europe.


Patient selection: acute-on-chronic liver failure (ACLF)

 

Parameter:

(1) leukocyte count in 10^9/L from 1 to 19

(2) prior history of acute decompensation

 

Group

28-Day Mortality

no ACLF

(0.001245 * (LC)) + 0.01763

ACLF with prior acute decompensation

(0.0007386 * ((LC)^2)) + (0.007477 * (LC)) + 0.225

ACLF with no prior acute decompensation

(0.001142 * ((LC)^2)) + (0.01391 * (LC)) + 0.3585

 


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