Description

Newman and Maisels used the maximum total serum bilirubin to predict the probability that a neonate with hyperbilirubinemia would develop a reduced intelligence quotient (IQ). The authors are from the University of California San Francisco and William Beaumont Hospital in Royal Oak, Michigan.


 

Endpoint: IQ < 90

 

predicted odds of an IQ < 90 =

= EXP(X)

 

X =

= (0.0347 * (total serum bilirubin in mg/dL)) - 1.0561

 

probability of an IQ < 90 =

= (predicted odds) / (1 + (predicted odds))

 

According to Dennery et al, boys are more susceptible to the adverse effects of neonatal hyperbilirubinemia than girls.

 


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