Cao et al reported prognostic factors for a patient with lung metastasis from a nasopharyngeal carcinoma. This can help to identify a patient who may require more aggressive management. The authors are from Sun Yat-sen University in Guangzhou, China.
Parameter:
(1) age in years
(2) T status
(3) N status
(4) lung metastases
(5) secondary metastases
(6) disease-free interval in months
(7) IgA antibodies against EBV viral capsid antigen (VCA-IgA)
(8) number of lung metastases
Parameter
Finding
Points
age in years
<= 45 years
0
> 45 years
1
T status
T1 or T2
0
T3 or T4
1
N status
N0 or N1
0
N2 or N3
1
lung metastases
unilateral
0
bilateral
1
secondary metastases
no
0
yes
1
disease-free interval
<= 24 months
1
> 24 months
0
VCA-IgA
<= 1:320
0
> 1:320
1
number of metastases
solitary
0
multiple
1
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 8
Total Score
Risk Group
5-Year Overall Survival
0 or 1
low
60%
2 or 3
intermediate
30%
4 to 8
high
7%
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