Perez et al identified prognostic factors for a woman with a squamous cell carcinoma of the cervix treated with radiation alone. The authors are from the Mallinckrodt Institute of Radiology and Washington University in Saint Louis.
Patient selection: invasive squamous cell carcinoma treated with radiation alone, stages IB to III
Parameters:
(1) FIGO stage
(2) size in centimeters
(3) parametrium extension
Stage
Size
Parametrium
Pelvic Recurrence
IB
< 3 cm
6%
IB
3 to 5 cm
15%
IB
> 5 cm
30%
IIA
< 3 cm
10%
IIA
3 to 5 cm
28%
IIA
> 5 cm
20%
IIB
<=5 cm, unilateral
20%
IIB
<= 5 cm bilateral
28%
IIB
> 5 cm, unilateral
35%
IIB
medial
20%
IIB
lateral
28%
IIB
bilateral
21%
III
<= 5 cm, unilateral
28%
III
> 5 cm, unilateral
45-50%
III
unilateral
28%
III
bilateral
48%
where:
• Bulky indicates > 5 cm in diameter
Stage
Size
Parametrium
5-Year DFS
IB
<= 3 cm
90%
IB
> 3 cm
67%
IIA
<= 3 cm
70%
IIA
> 3 cm
45%
Stage
Size
Parametrium
10-Year DFS
IIB
<=5 cm
65-70%
IIB
> 5 cm, bilateral
45-55%
III
<=5cm, unilateral
55%
III
> 5 cm, bilateral
35-40%
III
bilateral
35-40%
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