Prognostic Factors of Rodriguez-Galindo et al for a Patient with Ewing Sarcoma (St. Jude Children's Research Hospital Risk Stratification Scheme)

Description

Rodriguez-Galindo et al evaluated prognostic factors in patients with a tumor in the Ewing Sarcoma Family of Tumors (ESFT). These can help identify a patient who may benefit from more aggressive or a novel therapy. The authors are from St. Jude Research Hospital in Memphis, Tennessee.

Factors associated with metastasis at the time of diagnosis:

(1) diameter >= 8 cm

(2) primary site axial or pelvic (non-extremity)

Parameters affecting survival:

(1) age of the patient in years

(2) extent

Extent	Age in Years	Risk Group
localized	< 14 years	favorable
localized	>= 14 years	intermediate
metastases to lung only	NA	unfavorable, pulmonary
metastases to extra-pulmonary sites	NA	unfavorable, extra-pulmonary

where:

• Common extrapulmonary sites for metastasis are bone or bone marrow.

Risk Group	5 Year Overall Survival
favorable	88%
intermediate	65%
unfavorable, pulmonary	54%
unfavorable, extra-pulmonary	27%

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Prognostic Factors of Rodriguez-Galindo et al for a Patient with Ewing Sarcoma (St. Jude Children's Research Hospital Risk Stratification Scheme)

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