Amano et al reported a model for predicting the prognosis of a patient undergoing the resection of hepatic metastases from a colorectal carcinoma. This can help to identify a patient who may benefit from a more aggressive or novel therapy. The authors are from Osaka City University Graduate School of Medicine in Japan.
Patient selection: status post resection of hepatic metastases from a colorectal carcinoma
Parameters:
(1) H-factor classification of the Japanese Classification of Colorectal Carcinoma (JCCRC)
(2) N and M status from TNM classification
Number of Liver Metastases
Maximum Size in cm
H-Factor
none
NA
H0
1 to 4
<= 5 cm
H1
1 to 4
> 5 cm
H2
>= 5
<= 5 cm
H2
>= 5
> 5 cm
H3
N and M status:
(1) N0: nonoe
(2) N1: 1 to 3 pericolic/perirectal or intermediate lymph nodes
(3) N2: >= 4 pericolic/perirectal or intermediate lymph nodes
(4) N3: main or lateral lymph nodes
(5) M1: distant other than liver and/or peritoneum
N and M Status
H-Factor
Grade
N0 or N1
H1
A
N0 or N1
H2
B
N0 or N1
H3
C
N2
H1
B
N2
H2 or H3
C
N3
NA
C
M1
NA
C
Grade
Median Survival Time
5-Year Survival
A
72 months
59%
B
41 months
38.6%
C
23 months
0%
To read more or access our algorithms and calculators, please log in or register.
