Description

Fang et al reported a nomogram for predicting survival of a pediatric patient with a medulloblastoma. The authors are from Shanghai Jiao Tong University and Fujian Medical University in China.


Patient selection: pediatric patient with medulloblastoma, status post surgical repair

 

Parameters:

(1) diameter of the tumor in cm

(2) chemotherapy

(3) brainstem involvement

 

points for size =

= MAX(0,(15.385 * (size)) - 23.077)

 

Parameter

Finding

Points

chemotherapy

no

40.32

 

yes

0

brainstem involvement

no

0

 

yes

32

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 172.42

 

value of X =

= (-0.0001595 * ((score)^2)) - (0.02124 * (score)) + 2.32

 

probability of 5-year survival =

= 1 / (1 + EXP((-1) * X))

 

Performance:

• The area under the ROC curve is 0.77 for the training and 0.70 for the validation cohorts.


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