Prognostic Nomogram of Gold et al for a Gastrointestinal Stromal Tumor (GIST)

Description

Gold et al developed a prognostic nomogram for a patient with a primary gastrointestinal tumor (GIST). These can help to identify a patient who may benefit from more aggressive management. The authors are from multiple hospitals in the United States and Spain.

Patient selection: primary GIST following complete surgical excision

Parameters:

(1) diameter in centimeters

(2) mitotic rate per 50 high power microscopic fields (hpf)

(3) site

Diameter	Points
< 15 cm	(-0.198 * ((diameter)^2)) + (7.826 * (points)) - 0.07
>= 15 cm	49.73 + (1.007 * (diameter))

where:

• The diameter in the nomogram goes to 50 cm or 0.5 meter.

Parameter	Finding	Points
mitotic rate	0 to 4 per 50 hpf	0
	>= 5 per 50 hpf	81
location	stomach	0
	colon or rectum	6
	small bowel	39
	other	0

total score =

= SUM(points for all 3 parameters)

Interpretation:

• minimum score: 0

• maximum score: 220

• The higher the score the worse the prognosis.

Total Score	Percent with 5-Year Recurrence Free Survival
< 33	> 90%
33 to 83	(-0.007134 * ((points)^2)) + (0.227 * (points)) + 90.38
83 to 130	149.6 - (1.081 * (points))
> 130	< 10%

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Description

Specialty

ICD-10