Gimotty et al developed a prognostic tree for evaluating patients with thin primary cutaneous malignant melanomas. This can help identify patients who will require closer monitoring. The authors are from the University of Pennsylvania in Philadelphia.
Patient selection: thin melanoma (<= 1.0 mm)
Parameters:
(1) mitotic rate
(2) growth phase
(3) gender
Mitotic Rate |
Growth Phase |
Gender |
Risk Group |
0 |
radial |
NA |
minimal |
0 |
vertical |
NA |
low |
> 0 |
NA |
female |
moderate |
> 0 |
NA |
male |
high |
where:
• The mitotic rate is only described as 0 or not. There is no description of number of microscopic fields examined, or microscopic field area. This implies that any mitotic activity conveys risk.
Risk Group |
10 Year Risk of Metastasis |
minimal |
0.5% |
low |
4% |
moderate |
12.5% |
high |
31% |
Specialty: Hematology Oncology, Surgery, general, Dermatology