Albertsen et al studied survival for men with prostate cancer that was clinically localized and which was treated conservatively. Conservative treatment involves either no therapy, immediate hormonal therapy, or delayed hormonal therapy. This can give a baseline against which more aggressive therapy can be compared.
In general, over a 15 year period following initial diagnosis:
(1) Patients with a Gleason score of 2 to 4 face a minimal risk of death from prostate cancer.
(2) Patients with a Gleason score of 5 or 6 face a modest risk of death from prostate cancer that increases slowly.
(3) Patients with a Gleason score of 7 to 10 face a high risk of death from prostate cancer.
Men Aged 55 – 59 At Diagnosis
Gleason |
Percent Survival After Interval in Years |
|||||
---|---|---|---|---|---|---|
Score |
2.5 |
5 |
7.5 |
10 |
12.5 |
15 |
2-4 |
98 |
93 |
87 |
82 |
75 |
69 |
5 |
98 |
93 |
87 |
82 |
75 |
67 |
6 |
97 |
91 |
83 |
75 |
67 |
57 |
7 |
86 |
68 |
52 |
36 |
24 |
15 |
8-10 |
75 |
50 |
28 |
15 |
7 |
3 |
Gleason |
Percent Mortality due to Prostate Cancer |
|||||
---|---|---|---|---|---|---|
Score |
2.5 |
5 |
7.5 |
10 |
12.5 |
15 |
2-4 |
0 |
1 |
2 |
2 |
3 |
4 |
5 |
0 |
1 |
2 |
2 |
3 |
6 |
6 |
2 |
3 |
6 |
10 |
13 |
18 |
7 |
11 |
26 |
39 |
52 |
63 |
70 |
8-10 |
21 |
45 |
65 |
77 |
83 |
87 |
Men Aged 60 – 64 At Diagnosis
Gleason |
Percent Survival After Interval in Years |
|||||
---|---|---|---|---|---|---|
Score |
2.5 |
5 |
7.5 |
10 |
12.5 |
15 |
2-4 |
95 |
88 |
81 |
72 |
63 |
55 |
5 |
95 |
88 |
81 |
72 |
63 |
53 |
6 |
94 |
85 |
75 |
64 |
53 |
41 |
7 |
87 |
67 |
50 |
34 |
23 |
14 |
8-10 |
75 |
50 |
21 |
15 |
7 |
3 |
Gleason |
Percent Mortality due to Prostate Cancer |
|||||
---|---|---|---|---|---|---|
Score |
2.5 |
5 |
7.5 |
10 |
12.5 |
15 |
2-4 |
0 |
1 |
2 |
3 |
4 |
5 |
5 |
0 |
2 |
3 |
4 |
5 |
8 |
6 |
2 |
5 |
9 |
14 |
18 |
23 |
7 |
8 |
22 |
35 |
40 |
56 |
62 |
8-10 |
21 |
42 |
60 |
72 |
78 |
81 |
Men Aged 65 – 69 At Diagnosis
Gleason |
Percent Survival After Interval in Years |
|||||
---|---|---|---|---|---|---|
Score |
2.5 |
5 |
7.5 |
10 |
12.5 |
15 |
2-4 |
91 |
81 |
69 |
60 |
47 |
38 |
5 |
91 |
81 |
69 |
60 |
47 |
35 |
6 |
91 |
76 |
63 |
49 |
36 |
25 |
7 |
83 |
65 |
45 |
30 |
18 |
11 |
8-10 |
74 |
48 |
26 |
15 |
7 |
3 |
Gleason |
Percent Mortality due to Prostate Cancer |
|||||
---|---|---|---|---|---|---|
Score |
2.5 |
5 |
7.5 |
10 |
12.5 |
15 |
2-4 |
1 |
2 |
2 |
4 |
5 |
6 |
5 |
1 |
2 |
2 |
5 |
7 |
10 |
6 |
2 |
8 |
12 |
17 |
22 |
27 |
7 |
8 |
20 |
32 |
42 |
49 |
53 |
8-10 |
19 |
38 |
54 |
65 |
70 |
72 |
Men Aged 70 – 74 At Diagnosis
Gleason |
Percent Survival After Interval in Years |
|||||
---|---|---|---|---|---|---|
Score |
2.5 |
5 |
7.5 |
10 |
12.5 |
15 |
2-4 |
85 |
72 |
57 |
41 |
31 |
20 |
5 |
85 |
72 |
57 |
41 |
31 |
18 |
6 |
85 |
64 |
47 |
33 |
21 |
11 |
7 |
81 |
59 |
40 |
25 |
12 |
7 |
8-10 |
74 |
48 |
23 |
11 |
3 |
2 |
Gleason |
Percent Mortality due to Prostate Cancer |
|||||
---|---|---|---|---|---|---|
Score |
2.5 |
5 |
7.5 |
10 |
12.5 |
15 |
2-4 |
2 |
2 |
3 |
4 |
5 |
7 |
5 |
2 |
2 |
5 |
6 |
8 |
11 |
6 |
3 |
10 |
17 |
22 |
25 |
30 |
7 |
7 |
17 |
26 |
32 |
39 |
42 |
8-10 |
15 |
32 |
46 |
55 |
59 |
60 |
Purpose: To evaluate the risk for a man with localized prostate cancer treated conservatively.
Specialty: Hematology Oncology, Surgery, general, Urology
Objective: risk factors, severity, prognosis, stage
ICD-10: C61,