Gonzales et al used a ratio of lipoproteins to identify patients with hypertriglyceridemia who may be at risk for pancreatitis. The authors are from the Mayo Clinic.
Patient selection: serum hypertriglyceridemia (> 500 mg/dL)
Outcomes: episodes of pancreatitis
Parameters:
(1) serum triglyceride concentration
(2) serum apolipoprotein B concentration
ratio =
= (serum triglyceride) / (apolipoprotein B)
Interpretation:
• The results may show a range of values.
• A ratio < 10.6 is associated with a low probability of developing pancreatitis (1.5%), with a negative predictive value of 98.5%
Performance:
• The area under the ROC curve is 0.87.
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Specialty: Gastroenterology
