Engelhardt et al reported the Revised Myeloma Comorbidity Index (R-MCI). This is based on the Initial MCI (Freiburger Index of Kleber et al). The authors are from the University of Freiburg, Universite de Nantes, University Hospital Wurzburg, University Rotterdam and Memorial Sloan-Kettering Cancer Center.
Patient selection: multiple myeloma
Parameters:
(1) lung disease
(2) eGFR in mL per min per 1.73 sq m (using MDRD)
(3) Karnofsky performance status
(4) age in years
(5) frailty
(6) unfavorable cytogenetics
Parameter
Finding
Points
lung disease
none or mild
0
moderate or severe
1
eGFR
>= 60
0
< 60
1
Karnofsky PS
100%
0
80 to 90%
2
<= 70%
3
age
< 60 years
0
60 to 69 years
1
>= 70 years
2
frailty
none or mild
0
moderate or severe
1
unfavorable cytogenetics
no
0
yes
1
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 9
• The patient is considered fit if the score is <= 3 points.
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