Risk Factor of Michetti et al for Reintubation in a Surgical or Trauma Patient

Patient selection: surgical or trauma patient

Outcome: reintubation, with 60% within 48 hours of extubation and 76% within 96 hours

Risk factors for reintubation:

(1) older age (with age showing overlap between failed and successful extubation)

(2) delirium (odds ratio 3.0)

(3) moderate or copious secretions (odds ratio 4.0)

(4) oral/enteral opioid on day of extubation (odds ratio 4.2, most often oxycodone)

The mortality rate was 16% in reintubation patients, which is 5 times higher than for successful extubation.