Shalaby et al reviewed the effectiveness of radioiodine (I-131) therapy for a patient with Graves' disease. They identified factors associated with therapeutic failure. The authors are from Tulane University.
Patient selection: Graves' disease
Predictors for I-131 failure:
(1) male sex (relative risk 1.2)
(2) I-131 therapy >= 6 months after diagnosis of Graves' disease (relative risk 2.1)
(3) history of anti-thyroid drugs (relative risk 2.1)
(4) thyroid gland size
(5) RAI uptake in percent
Thyroid Gland Size
RAI Uptake
Outcome
>= 35.77 mL
NA
failure (RR 2.54)
< 35.77 mL
>= 60.62%
failure (RR 1.5)
< 35.77
< 60.62%
successful therapy
To read more or access our algorithms and calculators, please log in or register.
