Risk Factors of Boling et al for Perioperative Complications Associated with Transnasal Endoscopic Resection of a Pituitary Adenoma

Description

Boling et al identified risk factors associated with perioperative complications in patients undergoing transnasal endoscopic resection of a pituitary adenoma. These can help to identify a patient who may benefit from more aggressive management. The authors are from multiple institutions in the United States, Canada and Australia.

Patient selection: transnasal endoscopic resection of a pituitary adenoma

Outcome: perioprative complication (one or more occurred in 24% of patients)

Risk Factor	Associated Complication
extrapituitary extension	deep vein thrombosis, cardiac, cranial nerve damage
intraventricular extension	systemic, intracranial, reoperation, postoperative CSF leak
extension into anterior fossa	intracranial bleed
age of the patient <= 64 years of age	reoperation, postoperative CSF leak, readmission
female gender	postoperative CSF leak
body mass index >= 30 kg per sq m	postoperative CSF leak
previous radiation	pneumocephalus, internal carotid artery injury, other intracranial
liver disease	cardiac

Systemic complications included deep vein thrombosis, respiratory complications including pneumonia, and cardiac complications.

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Risk Factors of Boling et al for Perioperative Complications Associated with Transnasal Endoscopic Resection of a Pituitary Adenoma

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