Risk Factors of Dauplat et al for Distant Metastases in a Woman with an Epithelial Ovarian Carcinoma

 

Patient selection: woman with an epithelial ovarian carcinoma

 

Risk factors for distant metastases (including liver and nonregional lymph nodes):

(1) malignant ascites

(2) peritoneal carcinomatosis (disseminated tumor nodules throughout the peritoneal cavity including the liver capsule and diaphragm)

(3) large intra-abdominal metastasis (> 10 cm in diameter), especially when in the upper abdomen

(4) retroperitoneal lymph node involvement at the time of initial cancer surgery

 

Tumors with these features would be of a higher grade and stage.

 

Sites of distant metastases in the study:

(1) pleura

(2) liver

(3) lung

(4) nonregional lymph nodes (regional lymph nodes were pelvic and para-aortic groups)

(5) skin

(6) pericardium

(7) central nervous system

(8) bone