Karampatsas et al reported risk factors for late onset invasive Group B Streptococcal disease. These can help to identify a patient who should be more closely monitored. The authors are from St. George's University of London, Norwegian University of Science and Technology, UK Health Security Agency MRC/UVRI Uganda Research Unit and Public Health England.
Patient selection: late-onset invasive group B Streptococcal disease (LOGBS), Streptococcus agalactiae
Time of onset: 1 week to 3 months
Presentations: sepsis, meningitis or other invasive infection
Predictors of LOGBS:
(1) prematurity (OR 5.66), born at < 34 weeks
(2) low birth weight (OR 6.73), with birth weight < 2,500 g
(3) maternal colonization with Group B Streptococcus (OR 2.67)
(4) multiple gestation pregnancy (OR 8.01)
The risk of LOGBS increases with the number of risk factors present.
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