Patient selection: outpatient parenteral antibiotic therapy
Criteria for an adverse event:
(1) change in antimicrobial agent
(2) stopping antimicrobial therapy early
(3) readmission due to adverse drug event
(4) Clostridium difficile disease
Risk factors for higher risk of an adverse events:
(1) female sex
(2) therapy with daptomycin or vancomycin
(3) days on OPAT < 14 days
Risk factors for lower risk of an adverse event:
(1) therapy for uncomplicated bacteremia
(2) empiric therapy (not targeting a specific bacteria, fungus or virus)
The findings indicate that the patient should be closely monitored in the 2 weeks after hospital discharge.
