Risk factors:
(1) delay in diagnosis
(2) development of dengue hemorrhagic or dengue shock syndrome
(3) fluid overload during resuscitation
(4) pre-existing heart failure
(5) electrolyte imbalance, especially hyperkalemia
(6) acidosis
(7) pre-existing coagulopathy (uremic, other)
(8) pre-existing gastrointestinal ulceration or bleeding site
(9) protein malnutrition, with hypoalbuminemia
Management should include:
(1) careful monitoring of fluid input and output, weight and central venous pressure
(2) continuous renal replacement therapy