Singh et al evaluated solid organ transplant recipients who developed zygomycosis. They identified risk factors associated with infection and treatment outcome. The authors are from multiple university hospitals in North America and Europe.
Patient selection: solid organ transplant recipients
Reported mortality rates of solid organ recipients with zygomycosis: 49 to 71%
Risk factors for developing zygomycosis:
(1) renal failure at baseline
(2) diabetes mellitus
(3) history of therapy with voriconazole and/or caspofungin
Protective factors (reduced risk for developing zygomycosis):
