A critically-ill pediatric patient in the intensive care unit (PICU) may be at increased risk for developing a central line associated bloodstream infection (CLABSI). Woods-Hill et al identified risk factors for these infections. The authors are from The Children's Hospital of Philadelphia and the University of Pennsylvania.
Patient selection: pediatric patient in the intensive care unit
Outcome: central line associated bloodstream infection (CLABSI)
Risk factors for infection on multivariate analysis:
(1) number of central line accesses in the 3 days prior to infection onset
(2) acute behavioral health needs (psychiatry consult; antipsychotic medication for agitation or delirium, other)
(3) duration of central venous catheter (CVC) in days
(4) hematologic or immunologic disease
Parameter
Finding
Odds Ratio
number of accesses
< 80
1
>= 80
4.8
acute behavioral health needs
no
1
yes
3.2
duration of CVC
less than 8 days
1
8 to 14 days
4.2
15 to 29 days
9.8
30 to 59 days
17.3
60 to 89 days
39.8
>= 90 days
4.9
diagnosis
hematologic or immunologic
1.5
other
1
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