Risk Factors of Yokoyama et al for Venous Thromboembolism in a Japanese Patient with Diffuse Large B-Cell Lymphoma

 

Patient selection: Japanese patient with diffuse large B-cell lymphoma (DLBCL)

 

The key risk factor for venous thromboembolism was the ECOG status, with risk increased for ECOG stages 2, 3 and 4. The risk tended to increase as the patient became more debilitated and bed-ridden.

 

Additional risk factors discussed:

(1) age >= 60 years

(2) presence of a central venous catheter

(3) venous compression by the bulky lymphoma

(4) elevated serum LDH

 

A patient with one or more risk factors (especially high ECOG stage) may benefit from more aggressive management.