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Risk Factors of Zhang et al for Early Postoperative Cognitive Dysfunction (POCD) After Colorectal Surgery

Description

Zhang et al identified risk factors for early Postoperative Cognitive Dysfunction (POCD) in older adults undergoing colorectal surgery. These can help to identify a patient who may require more aggressive management. The authors are from Nanjing First Hospital in China.


Patient selection: adult after colorectal surgery for colon cancer, age >= 65 years

 

Exclusions: postoperative delirium, drugs causing cognitive impairment, neurological or psychiatric disorders

 

Outcome: deterioration in cognition, as measured on day 7 after surgery

 

Cognitive testing: MMSE, VVLT (visual verbal learning test), DST1 (digital span test), DST2 (digital symbol test)

 

Risk factors for POCD:

(1) diabetes mellitus (odds ratio 8.4)

(2) fasting for >= 3 days after surgery (odds ratio 5.2)

(3) SIRS score 3 or 4 on the second day after surgery (range 0 to 4; odds ratio 7.0)


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