Wallgren et al listed the risk for locoregional recurrence in a woman treated for breast cancer. The authors are from multiple universities participating in the International Breast Cancer Study Group (IBCSG).
There are 6 groupings of patients based on:
(1) menopausal status
(2) number of axillary lymph nodes with metastases
Data used:
(1) diameter of the tumor in cm
(2) lymphovascular invasion
(3) histologic grade (from 1 to 3)
Premenopausal with no lymph node metastases
Diameter |
Lymphovascular Invasion |
Risk |
---|---|---|
<= 2 cm |
absent |
low |
<= 2 cm |
present |
moderate to high |
> 2 cm |
absent |
moderate to high |
> 2 cm |
present |
very high |
Premenopausal with 1 to 3 lymph node metastases
Lymphovascular Invasion |
Histologic Grade |
Risk |
---|---|---|
absent |
1 |
low |
absent |
2 |
low |
absent |
3 |
low |
present |
1 |
low |
present |
2 |
moderate |
present |
3 |
high |
Premenopausal with 4 or more lymph node metastases
Lymphovascular Invasion |
Histologic Grade |
Risk |
---|---|---|
absent |
1 |
moderate |
absent |
2 |
high |
absent |
3 |
high |
present |
1 |
high |
present |
2 |
very high |
present |
3 |
very high |
Postmenopausal with no lymph node metastases
Lymphovascular Invasion |
Risk |
---|---|
absent |
low to moderate |
present |
high to very high |
Postmenopausal with 1 to 3 lymph node metastases
Diameter |
Histologic Grade |
Risk |
---|---|---|
<= 2 cm |
1 |
low |
<= 2 cm |
2 |
low |
<= 2 cm |
3 |
moderate |
> 2 cm |
1 |
low |
> 2 cm |
2 |
moderate |
> 2 cm |
3 |
high |
Postmenopausal with 4 or more lymph node metastases
Diameter |
Histologic Grade |
Risk |
---|---|---|
<= 2 cm |
1 |
high |
<= 2 cm |
2 |
high |
<= 2 cm |
3 |
very high |
> 2 cm |
1 |
high |
> 2 cm |
2 |
very high |
> 2 cm |
3 |
very high |
Purpose: To evaluate a woman who has been treated for breast cancer for the risk of locoregional recurrence based on the report of Wallgren et al.
Specialty: Hematology Oncology, Surgery, general, Obstetrics & Gynecology
Objective: risk factors, severity, prognosis, stage, response to therapy
ICD-10: C50,