Tsai et al evaluated patients for acute kidney injury following a percutaneous coronary intervention (PCI). One model predicts acute kidney injury (AKI) while a second predicts AKI requiring dialysis. The authors are from multiple institutions in the United States using the National Cardiovascular Data Registry Cath-PCI Registry.
Patient selection: status post percutaneous coronary intervention (PCI)
Outcome: acute kidney injury
Parameters:
(1) heart failure in the prior 2 weeks
(2) GFR in mL per min
(3) diabetes mellitus
(4) coronary artery disease
(5) prior cardiac arrest
Parameter |
Finding |
Points |
heart failure |
no |
0 |
|
yes |
2 |
GFR |
none (>= 60) |
0 |
|
mild (45 to 59.5) |
1 |
|
moderate (30 to 44.9) |
3 |
|
severe (< 30) |
5 |
diabetes |
no |
0 |
|
yes |
1 |
coronary artery disease |
no |
0 |
|
unstable angina |
1 |
|
NSTEMI |
1 |
|
STEMI |
2 |
prior cardiac arrest |
no |
0 |
|
yes |
3 |
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: 0
• maximum score: 13
• The higher the score the greater the risk.
Score |
Risk of AKI |
0 |
0.03% |
1 |
0.05% |
2 |
0.09% |
3 |
0.15% |
4 |
0.27% |
5 |
0.48% |
6 |
0.84% |
7 |
1.5% |
8 |
2.6% |
9 |
4.4% |
10 |
7.6% |
11 |
12.6% |
12 |
20.3% |
13 |
31% |
Performance:
• The area under the ROC curve is 0.89.
Specialty: Hematology Oncology, Cardiology, Nephrology