Description

Alberti et al developed a score for identifying an infected patient in the intensive care unit (ICU) who is likely to progress to severe sepsis or septic shock. These patients may benefit from more aggressive management. The author are from multiple medical centers in Europe and are members of the European Sepsis Study Group.


Parameters:

(1) heart rate

(2) systolic blood pressure

(3) body temperature

(4) mechanical ventilation

(5) pneumonia

(6) peritonitis

(7) primary bacteremia

(8) serum total bilirubin

(9) serum sodium

(10) platelet count

(11) Gram-positive cocci

(12) aerobic Gram-negative bacilli

 

Parameter

Finding

Points

heart rate

<= 120 per minute

0

 

> 120 per minute

3

systolic blood pressure

>= 110 mm Hg

0

 

< 110 mm Hg

4

body temperature

<= 38.2°C

0

 

> 38.2°C

5

mechanical ventilation

no

0

 

yes

6.5

pneumonia

absent

0

 

present

4

peritonitis

absent

0

 

present

4

primary bacteremia

absent

0

 

present

6

serum total bilirubin

<= 30 µmol/L

0

 

> 30 µmol/L

3

serum sodium

<= 145 mmol/L

0

 

> 145 mmol/L

4

platelet count

>= 150,000 per µL

0

 

< 150,000 per µL

4

Gram-positive cocci

absent

0

 

present

2.5

aerobic Gram-negative bacilli

absent

0

 

present

3

 

total score =

= SUM(points for all 12 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 49 (theoretical)

• The higher the score the greater the risk of severe sepsis or septic shock.

• The higher the score the greater the time spent in the ICU.

 

Total Score

Risk Group

Percent Who Worsen

0 to 8

low

9%

8.1 to 16

moderate

17%

16.1 to 24

high

31%

> 24

very high

55%

 


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