Description

Ducrocq et al developed a score for predicting serious bleeding in a patient at risk for atherothrombosis. This can help the physician to plan a safe and effective management strategy. The authors are REACH Investigators from multiple universities in France and the United States.


Patient selection: adult >= 45 years of age at risk for atherothrombosis

 

Outcome: serious bleeding defined as non-fatal hemorrhagic stroke or bleeding leading to hospitalization and transfusion

 

Parameters:

(1) age in years

(2) peripheral arterial disease

(3) congestive heart failure (CHF)

(4) diabetes

(5) hypercholesterolemia

(6) hypertension

(7) smoking

(8) antiplatelet therapy

(9) oral anticoagulants

 

Parameter

Findings

Points

age in years

45 to 54 years old

0

 

55 to 64 years old

2

 

65 to 74 years old

4

 

>= 75 year old

6

peripheral arterial disease

no

0

 

yes

1

congestive heart failure

no

0

 

yes

2

diabetes

no

0

 

yes

1

hypercholesterolemia

no

1

 

yes

0

hypertension

no

0

 

yes

2

smoking

never

0

 

former

1

 

current

2

antiplatelet therapy

none

0

 

ASA

1

 

other

2

 

both

4

oral anticoagulants

no

0

 

yes

4

 

where:

• Hypercholesterolemia is scored the opposite for risk of atherosclerosis.

• Former smoking could be from 1 week to 50 years.

 

total score =

= SUM(points for

 

Interpretation:

• minimum score: 0

• maximum score: 23

• The higher the score the greater the risk of serious bleeding.

 

Total Score

Incidence of Bleeding at 2 Years

0 to 6

0.46%

7 or 8

0.95%

9 or 10

1.25%

11 to 23

2.76%

 


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