Ducrocq et al developed a score for predicting serious bleeding in a patient at risk for atherothrombosis. This can help the physician to plan a safe and effective management strategy. The authors are REACH Investigators from multiple universities in France and the United States.
Patient selection: adult >= 45 years of age at risk for atherothrombosis
Outcome: serious bleeding defined as non-fatal hemorrhagic stroke or bleeding leading to hospitalization and transfusion
Parameters:
(1) age in years
(2) peripheral arterial disease
(3) congestive heart failure (CHF)
(4) diabetes
(5) hypercholesterolemia
(6) hypertension
(7) smoking
(8) antiplatelet therapy
(9) oral anticoagulants
Parameter |
Findings |
Points |
---|---|---|
age in years |
45 to 54 years old |
0 |
|
55 to 64 years old |
2 |
|
65 to 74 years old |
4 |
|
>= 75 year old |
6 |
peripheral arterial disease |
no |
0 |
|
yes |
1 |
congestive heart failure |
no |
0 |
|
yes |
2 |
diabetes |
no |
0 |
|
yes |
1 |
hypercholesterolemia |
no |
1 |
|
yes |
0 |
hypertension |
no |
0 |
|
yes |
2 |
smoking |
never |
0 |
|
former |
1 |
|
current |
2 |
antiplatelet therapy |
none |
0 |
|
ASA |
1 |
|
other |
2 |
|
both |
4 |
oral anticoagulants |
no |
0 |
|
yes |
4 |
where:
• Hypercholesterolemia is scored the opposite for risk of atherosclerosis.
• Former smoking could be from 1 week to 50 years.
total score =
= SUM(points for
Interpretation:
• minimum score: 0
• maximum score: 23
• The higher the score the greater the risk of serious bleeding.
Total Score |
Incidence of Bleeding at 2 Years |
---|---|
0 to 6 |
0.46% |
7 or 8 |
0.95% |
9 or 10 |
1.25% |
11 to 23 |
2.76% |
Purpose: To determine the risk of serious bleeding in an adult at risk for atherothrombosis using the score of Ducrocq et al.
Specialty: Hematology Oncology, Clinical Laboratory, Pharmacology, clinical
Objective: risk factors, severity, prognosis, stage
ICD-10: I80, I81, I82,