Goriki et al reported a simple risk score for identifying a patient with acute myocardial infarction who is at risk for major bleeding. The authors are from Saga University and affiliated hospitals in Saga, Japan.
Patient selection: hospitalized patient after acute myocardial infarction
Outcome: major bleeding (severe or life-threatening; intracranial; hemodynamic compromise requiring treatment)
Parameters:
(1) hemoglobin in g/dL
(2) white blood cell count per microliter
(3) platelet count per microliter
(4) serum albumin in g/dL
(5) eGFR in mL per min per 1.73 square meters
Parameter
Finding
Points
hemoglobin
>= 12 g/dL
0
< 12 g/dL
1
WBC count
<= 10,000 per µL
0
> 10,000 per µL
1
platelet count
>= 150,000 per µL
0
< 150,000 per µL
1
serum albumin
>= 3.8 g/dL
0
< 3.8 g/dL
1
eGFR
>= 60 mL/min/1.73 sq m
0
< 60 mL/min/1.73 sq m
1
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 5
Total Score
Risk Category
Rate of Major Bleeding
0 or 1
low
2.5-3.4%
2 or 3
moderate
14-15%
4 or 5
high
47-51%
Performance:
• The area under the ROC curve is 0.80.
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