Description

Sabatine et al developed a risk score for patients with unstable angina pectoris. This can help identify patients who have a survival benefit associated with therapy with glycoprotein IIb/IIIa inhibitor therapy. The authors are from Massachusetts General Hospital, Montreal Heart Institute and Merck Research Laboratories.


Parameters:

(1) age in years

(2) history of coronary artery bypass

(3) antecedent aspirin use

(4) antecedent beta-blocker use

(5) ST wave on presenting ECG

 

Parameter

Finding

Points

age in years

<= 65 years of age

0

 

> 65 years of age

1

history of coronary artery bypass surgery

absent

0

 

present

1

antecedent aspirin use

absent

0

 

present

1

antecedent beta blocker use

absent

0

 

present

1

ST wave on presenting ECG

not depressed

0

 

depressed

1

 

total score =

= SUM(points for all 5 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 5

• A higher score indicates greater risk of an endpoint (myocardial infarction, death, refractory ischemia) at 7 days.

 

Total Score

Risk Group (Risk of Endpoint)

Benefit from heparin plus  IIb/IIIa inhibitor

0 or 1

low (7%)

none

2 or 3

intermediate (23%)

mild

4 or 5

high (37%)

moderate

 


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