Esophageal Cancer Mortality Risk Score 30 Day Mortality After Surgery

Description

Steyerberg et al developed a risk score for predicting mortality within 30 days of surgical resection of an esophageal cancer. This can help identify a patient who may benefit from an alternative or novel therapy. The authors are from Erasmus University (Rotterdam, NL), Eindhoven Comprehensive Cancer Center (Eindhoven, NL) and Dana-Farber Cancer Center (Boston, USA).

Parameters:

(1) age in years

(2) comorbidities (5)

(3) neoadjuvant therapy

(4) number of esophagectomies done per year at the hospital

Parameter	Finding	Points
age in years	50	-1
	65	0
	80	1
comorbidity, pulmonary	absent	0
	present	1
comorbidity, cardiovascular	absent	0
	present	1
comorbidity, diabetes	absent	0
	present	1
comorbidity, hepatic	absent	0
	present	1
comorbidity, renal	absent	0
	present	1
neoadjuvant therapy	chemoradiotherapy	1
	radiotherapy	1.5
annual hospital case volume	low (<= 1)	0
	intermediate (1.1 to 2.5)	-0.5
	high (2.6 to 49)	-1.5
	very high (>= 50)	-2

points for age =

= ((age in years) / 15) - (13 / 3) = (0.0667 * (age in years)) - 4.333

total score =

= SUM(points for all of the parameters)

X =

= (0.32 * (total score)) - 2.41

probability of 30-day surgical mortality =

= 1 / (1 + EXP((-1) * X))

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Description

Specialty

Objective

ICD-10

Risk Score of Steyerberg et al for 30 Day Mortality After Surgery for Esophageal Cancer

Purpose: To evaluate a patient for 30-day surgical mortality following resection of an esophageal cancer based on the risk score of Steyerberg et al.

Description

Specialty

Objective

ICD-10