Thiel et al used recursive partitioning and regression tree (RPART) analysis to identify hospitalized patients at risk for septic shock. One analysis included results without arterial blood gas analysis. The authors are from Washington University and Barnes-Jewish Hospital in St Louis.
Patient selection: hospitalized patient not in ICU
Parameters:
(1) shock index (SI)
(2) white blood cell count per µL
(3) mean arterial pressure in mm Hg
(4) INR
(5) serum sodium in mmol/L
(6) serum total bilirubin in mg/dL
(7) hemoglobin in g/dL
(8) serum albumin in g/dL
(9) absolute neutrophil count per µL
Findings associated with septic shock:
(1) SI >= 1.2, MAP < 68, INR >= 1.5
(2) SI >= 1.2, MAP < 68, INR < 1.5, bilirubin < 0.4
(3) SI >= 1.2, MAP >= 68, WBC >= 15,600
(4) SI < 1.2, bilirubin >= 2.5, INR >= 1.5, albumin >= 3.2, hemoglobin < 11
(5) SI < 1.2, bilirubin >= 2.5, INR >= 1.5, albumin < 3.2, sodium >= 146
(6) SI < 1.2, bilirubin < 2.5, neutrophil count >= 16000, albumin < 2.5, hemoglobin >= 12
