The glomerular filtration rate (GFR) for a patient with cirrhosis can be estimated using the Royal Free Hospital equation. The authors are from the Royal Free Hospital, University College London, Aristotle University (Greece), and S. de Bellis Research Hospital (Italy)..
Patient selection: cirrhosis
Parameters:
(1) serum creatinine in µmol/L
(2) serum urea in mmol/L
(3) INR
(4) age in years
(5) serum sodium in mmol/L
(6) sex
(7) severity of ascites
Parameter
Finding
Points
creatinine
(creatinine)^(-0.836)
urea
(urea)^(-0.229)
INR
(INR)^(-0.113)
age
(age)^(-0.129)
sodium
(sodium)^(0.972)
sex
male
1
female
0.809
severity of ascites
none or mild
1
moderate or severe
0.92
GFR in mL per min per 1.73 square meter =
= 45.9 * PRODUCT(all 7 parameters)
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