RTOG/EORTC Criteria for Laryngeal Complications to Irradiation

Description

The Radiation Therapy Oncology Group (RTOG) and the European Organization for Research on the Treatment of Cancer (EORTC) provide criteria for assessing the complications of radiation therapy affecting the larynx.

Guidelines:

(1) Change in affected parameter is ascribed to radiation therapy and not underlying or concurrent disease.

(2) Considered acute if occurs from day 1 to 90; after day 90 considered late complication.

Acute Complications

Grade 0: none (no change from baseline)

Injury	Grade 1	Grade 2	Grade 3	Grade 4
hoarseness	mild or intermittent	persistent hoarseness but able to vocalize	whispered speech	marked dyspnea, stridor or hemoptysis
cough	does not require antitussives	requires antitussive	NA	NA
mucosa	erythema	patchy fibrinous exudate	confluent fibrinous exudate	NA
arytenoid edema	NA	mild	marked	NA
other	NA	sore throat or referred ear pain, not requiring narcotic	throat pain or referred ear pain, requiring narcotic	tracheostomy or intubation necessary

Grade 5: death directly due to radiation effect

Late Complications

Grade 0: no change from baseline

Injury	Grade 1	Grade 2	Grade 3	Grade 4
chondritis		moderate	severe	NA
arytenoid edema	mild	moderate	severe	NA
other	hoarseness	NA	NA	necrosis

Grade 5: death directly due to radiation late effect

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Description

Specialty

ICD-10