Sarcopenia and handgrip strength can help to identify a patient with worse prognosis.
Patient selection: cirrhosis
Sarcopenia or low handgrip strength are associated with:
(1) encephalopathy
(2) increased mortality
Gender
Handgrip Associated with Increased Mortality
female
< 18.8 kg
male
< 27.8 kg
Additional prognostic factors:
(1) reduced serum branched-chain amino acids (< 327 µmol/L)
(2) rapid muscle wasting
(3) elevated blood ammonia
The change in skeletal muscle area per year was associated with mortality. A change less then -3.1% was associated with better survival.
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Specialty: Gastroenterology
