Score of Plotkin et al for Determining Severity of Cytomegalovirus Infection in Renal Transplant Recipients

duration of fever

< 38.3°C orally or rectally

0

>= 38.3°C orally or rectally for 1 day

0

>= 38.3°C orally or rectally for 2 - 4 days (mild)

1

>= 38.3°C orally or rectally for 5 - 20 days (moderate)

1

>= 38.3°C orally or rectally for >= 21 days (severe)

3

leukopenia

>= 4,000 per µL

0

< 4,000 per µL

1

thrombocytopenia

>= 100,000 per µL

0

< 100,000 per µL

1

hepatitis

none

0

increase liver function tests >= 2 times normal

1

jaundice

3

pneumonia

none

0

infiltrate on chest X-ray

1

infiltrate and symptomatic

2

ventilator support

3

gastrointestinal tract

no bleeding or ulceration

0

bleeding or ulceration due to CMV (proven by biopsy)

3

CNS changes

none

0

lethargy

1

stupor

2

coma

3

renal

creatinine < 2 times above best level after transplantation

0

creatinine 2 - 4 times above best level after transplantation

1

creatinine > 4 times above best level after transplantation

2

nephrectomy

3

permanent dialysis

3

arthritis and/or muscle wasting

absent

0

present

2

superinfection

absent

0

present

3