Walker et al reported a screening tool for early recognition of bloodstream infection in an older adult. This can avoid a delay in diagnosis and therapy. The authors are from Sunnybrook Health Sciences Centre and University of Toronto.
Patient selection: hospitalized patient >= 65 years of age (derivation cohort >= 80 years of age)
Parameters:
(1) maximum temperature in °C
(2) absolute neutrophil count in 10^9/L
(3) change in level of consciousness (LOC)
(4) serum urea in mmol/L
(5) serum glucose in mmol/L
(6) serum albumin in g/L
(7) serum ALT in U/L
Parameter
Points
maximum temperature
3.751 * (temperature)
absolute neutrophil count
0.645 * (count)
change in level of consciousness
0.452 if yes, 0 if no
serum urea
0.307 * (urea)
serum glucose
0.154 * (glucose)
serum albumin
0.038 * (albumin)
serum ALT
0.005 * (ALT)
value of X =
= SUM(points for all of the parameters) - 150.299
probability of bloodstream infection =
= 1 / (1 + EXP((-1) * X))
Performance:
• The authors claim an area under the ROC curve of 0.945 (lower in the validation cohort).
To read more or access our algorithms and calculators, please log in or register.
