Severity of Acute Pancreatitis in Children, Systemic Inflammatory Response Syndrome (SIRS) and Serum C-Reactive Protein (CRP)

Patient selection: pediatric patient with acute pancreatitis

Criteria for acute pancreatitis - 2 or more of the following:

(1) abdominal pain compatible with acute pancreatitis

(2) serum amylase and/or lipase > 3 times upper limit of normal (ULN)

(3) imaging findings (US, CT, MRI) compatible with acute pancreatitis

Risk factors for severe acute pancreatitis on admission:

(1) SIRS

(2) serum CRP > 27.5 mg/L

Risk factors for SIRS:

(1) fever (a criteria for SIRS)

(2) coexisted diseases (sepsis, pneumonia, cholestatic hepatitis, Kawasaki disease)