Chee et al reported the SHARPEN clinical risk score to evaluate adults with infective endocarditis. This can help to identify a patient who may benefit from more aggressive management. The authors are from the National University of Singapore.
Acronym: SHARPEN
Parameters:
(1) systolic blood pressure at presentation (S)
(2) heart failure (H)
(3) age in years (A)
(4) raised serum creatinine in µmol/L (R)
(5) pneumonia (P)
(6) elevated peak serum C-reactive protein in mg/dL (E)
(7) non-intravenous drug abuser (N)
Parameter
Finding
Points
systolic blood pressure
>= 90 mm Hg
0
< 90 mm Hg
3
heart failure
absent
0
present
2
age in years
< 50 years
2
50 to 65 years
4
> 65 years
6
serum creatinine
<= 200 µmol/L
0
> 200 µmol/L
2
pneumonia
absent
0
present
2
serum CRP
<= 200 mg/dL
0
> 200 mg/dL
2
non-intravenous drug abuser
yes
3
no (intravenous drug abuser)
0
total score =
= SUM(points for all 7 parameters)
Interpretation:
• minimum score: 2
• maximum score: 20
Total Score
Risk Group
Mortality Rate
2 to 6
low
3%
7 to 10
moderate
14%
11 to 20
high
62% (100% if score >= 15)
Performance:
• The area under the ROC curve is 0.86.
To read more or access our algorithms and calculators, please log in or register.
