Peripheral nociceptive injury may be followed by development of a central pain syndrome.
Peripheral nociceptive injury involves damage to peripheral nociceptive nerve endings and can be seen with:
(1) small fiber neuropathy
(2) radiculopathy
(3) plexopathy (brachial, lumbosacral)
(4) complex regional pain syndrome
(5) inflammatory peripheral neuropathy
Clinical findings seen with nociceptive central pain:
(1) hypersensitivity to stimuli at the site of injury
(2) mechanoallodynia (pain triggered by a mechanical stimulus)
(3) thermal hyperalgesia
(4) hyperpathia
(5) extraterritoriality with regional distribution of pain (in complex regional pain syndrome or reflex sympathetic dystrophy)
(6) neurogenic inflammation inflammation, autonomic dysregulation, and/or motor phenomenona (in complex regional pain syndrome or reflex sympathetic dystrophy)
Purpose: To identify clinical features of central pain following damage to peripheral nociceptive nerve endings.
Specialty: Sports Medicine & Rehabilitation
Objective: clinical diagnosis, including family history for genetics
ICD-10: R52.1, R52.2,