SOFSURF Index to Identify a Postmenopausal Woman with Osteoporosis

 

Patient selection: postmenopausal female

 

Parameters:

(1) age in years

(2) weight in kilograms

(3) cigarette smoking

(4) history of post-menopausal fracture (or fracture after age 50)

Parameter	Finding	Points
age in years	< 65	0.2 * ((age) - 65)
	65	0
	> 65	0.2 * ((age) - 65)
body weight	>= 150 lbs (68 kg)	0
	130 to 149 lbs	1
	< 130 lbs (59 kg)	3
cigarette smoking	no	0
	yes	1
history of postmenopausal fracture	none	0
	present	1

 

where:

• The original abstract did not score age < 65 years. The study was done in women between 67 and 72 years.

• An age < 65 years yields negative points.

 

total score =

= SUM(points for all 4 parameters)

 

Interpretation:

• minimum score: -4 or lower (depends on age)

• maximum age: 12 or more (depends on age)

• The higher the index the greater the risk of osteoporosis.

• Black et al use a cutoff > 3 (which was the median score in the study).

• Koh et al used a cutoff of 1.4.

 

Performance:

• The score has a good sensitivity but low specificity, which is suitable for a simple screening tool.

• In the original abstract with a cutoff of 3, 85% of women with scores > 3 had a T score < -2.5.

• In the study of Koh et al, a cutoff of 1.4 had a sensitivity of 90% and specificity of 46% in a population of Asian women, with an AUC of 0.76.