Patient's with Wilson's disease may develop significant disability from neuropsychiatric involvement. Chu graded this disability based on clinical findings.
Parameters:
(1) involuntary movements
(2) oropharyngeal function
(3) gait
(4) rigidity or spasticity
(5) impairment
(6) psychiatric symptoms
Parameter |
Stage 0 |
Stage I |
Stage II |
Stage III |
involuntary movements |
none |
hand tremor |
moderate |
marked |
oropharyngeal function |
normal |
slurred speech, hoarse |
dysarthria, dysphagia |
NA |
gait |
normal |
tendency to fall |
unsteady |
bedridden, gross ataxia |
rigidity or spasticity |
none |
none to mild |
moderate |
marked |
impairment |
none |
none to mild |
moderate |
marked |
psychiatric symptoms |
baseline |
baseline to mild |
moderate to marked |
NA |
Purpose: To grade the severity of neurological involvement in a patient with Wilson's disease using Chu's staging system.
Specialty: Sports Medicine & Rehabilitation, Neurology
Objective: severity, prognosis, stage, disability and performance
ICD-10: E83.0,